The methylation cycle is a biochemical pathway that manages a wide range of functions in the body including detoxification, immune regulation, energy production, mood balancing and controlling inflammation, which help the body respond to its environment in a healthy way by reacting to environmental stressors appropriately and detoxifying the body. Dysfunction in the methylation cycle can cause a myriad of different conditions such as heart disease, cancer, diabetes, neurological conditions, autism, allergies, fertility issues, and mood disorders.
The study of nutrigenomics and epigenetics suggests that specific nutrients can impact gene expression. Proper nutrients are necessary to promote the correct expression of genes and thus the correct biochemical functioning of the body. By knowing what genes are affected, we can target the nutritional support to shift gene expression in the direction of healthy metabolism and biochemical processes needed for health.
There are detox profiles that can help you understand how your detox pathways are working, such as Genova’s detoxigenomic or neurogenomic profiles, but the most affordable and comprehensive way to find out about your genetic profile (and how it relates to your health) is through the website www.23andme.com. Once you get what is referred to as “raw data,” you can upload it to different websites for interpretation, some of which include: www.mthfrsupport.com, www.geneticgenie.org or www.nutrihacker.com, which will provide information about how the specific gene mutations influence your health, and what you can do about it. It is important that you do not try to treat yourself with this information, as starting supplementation can often lead to what is called over-methylation or over-mobilization of toxins, and often people will feel worse before feeling better, and it is a delicate balance to understand methylation and how to turn certain genes back on while not overloading the detox pathways.
There are comprehensive supplementation protocols that can help with a wide variety of gene mutations in detoxification. In addition to supplementation, avoiding certain foods can be equally as important. The understanding of how these foods influence your health, and how methylation support can greatly relieve some lifelong issues can be a life-changing experience. It is worthwhile to see a practitioner that is skilled in methylation and genomic medicine, and have a full evaluation done before starting methylation support, but there are a lot of resources available to help you gain a better understand of how this may be impacting your health and where you can go for help.
Some of these resources include:
MTHFR Support on Facebook Forums on www.phoenixrising.me